R&D Grade Plasmid DNA Production Services

MDS offers high throughput production to manufacture exactly what you require. Our experienced scientists can also provide you assistance in regulatory issues that will need to be addressed in order to move into pre-clinical production. Your plasmids will be purified without use of animal products in final formulation in the buffer of your choice at a specified concentration. Plasmids will meet full Quality Control Testing before delivery.

Pilot studies

To isolate large quantities of plasmid DNA, we recommend the use of high-copy-number plasmids. To estimate the total amount of plasmid DNA expected from each preparation, we recommend carrying out a pilot small-scale using 30-50 ml of the original culture. Optimal plasmid yields strictly depend on proper growth conditions (temperature, shaker speed, culture vessel, bacterial strain, induction conditions, and antibiotic concentration